Does Hepatitis Affect The Kidneys – Many people struggle to understand the connection between chronic hepatitis B (HBV) infection and non-alcoholic fatty liver disease (NAFLD). While research studies are ongoing and the relationship between hepatitis B and NAFLD is indeed complex, a chronic hepatitis B infection does not cause NAFLD. It is important to understand the two diseases independently of each other before studying their interrelationship.
Hepatitis B and fatty liver disease can both damage the liver. It is therefore important to understand the role of the liver in maintaining overall health and well-being. The liver is an essential organ in your body and is responsible for digestion and regulation of nutrients. It plays an important role in removing toxins from your body.
- 1 Does Hepatitis Affect The Kidneys
- 1.1 What Happens To Your Body When You Have Hepatitis C
- 1.2 Hepatitis B And Your Cancer Risk
- 1.3 Pdf) Project Help: A Study Protocol To Pilot Test A Shared Decision Making Tool About Treatment Options For Patients With Hepatitis C And Chronic Kidney Disease
Does Hepatitis Affect The Kidneys
Worldwide, approximately 300 million people live with hepatitis B. Hepatitis B is spread through direct contact with infected blood, unprotected sex with an infected person, the use of contaminated medical or injection equipment, and, most commonly, from an infected mother to her newborn baby. Child birth A chronic (lasting longer than six months) hepatitis B infection can damage the liver and progress to more serious conditions such as cirrhosis, fibrosis and even liver cancer. While hepatitis B is a major public health problem, it can be prevented with a safe and effective vaccine. And while hepatitis B is a serious disease, most people lead healthy and productive lives with effective management and treatment.
What Happens To Your Body When You Have Hepatitis C
NAFLD is caused by excessive accumulation of fat in the liver unrelated to alcohol consumption. Over time, this can lead to swelling or inflammation and liver damage. There are two types of NAFLD: 1). non-alcoholic fatty liver (NAFL) or simple fatty liver and 2) non-alcoholic steatohepatitis (NASH). A person with NAFL has a build-up of fat in the liver. Someone with NASH also has liver damage and inflammation of the liver, which can lead to cirrhosis, liver cancer, and may even lead to the need for a liver transplant. Type II diabetes and obesity put a person at a higher risk of developing NAFLD. In the United States, approximately 20% to 40% of individuals are living with NAFLD. The good news is that NAFLD can be reversed with changes in diet, physical activity patterns and regular visits to the doctor.
It is possible to have both NAFLD and hepatitis B. Living with both can cause liver damage due to the virus’ effect on an already inflamed and compromised liver. With excess fat stored in liver cells, the virus can easily replicate without the protection of healthy liver cells and can quickly progress to a more serious form of liver disease such as cirrhosis, fibrosis or cancer.
Like Hepatitis B, NAFLD should not be taken lightly as it can lead to serious health problems. It is important to consult your doctor to rule out any concerns related to your liver.
For more information, please visit the National Institute of Digestive and Kidney Diseases (NIDDK) or the Fatty Liver Foundation.
A Review Of Hepatitis B Virus And Hepatitis C Virus Immunopathogenesis
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And can treatment of the virus reduce the risk of chronic kidney and cardiovascular disease, as well as the risk of death from such causes?
Hepatitis C virus (HCV) may be a liver disease, but scientists increasingly understand that the virus can have deadly effects elsewhere in the body. (These are known as extrahepatic effects because they occur outside the liver.) For example, many research articles have determined that Hep C increases the risk of cardiovascular disease (CVD) and chronic kidney disease (CKD). is on dialysis.
First Functioning Kidney Tissue Generated From Embryonic Stem Cells
Even when individuals do not have Hep C, CVD is a major cause of morbidity and death in people with late-stage CKD and at a higher rate than in people with good kidney function. In recent years, researchers have identified Hep C as a risk factor for death in dialysis recipients, he said.
The good news is that individuals can control this particular risk by getting treatment for the virus. But a key question remains: Does HCV treatment reduce the risk of death in people on dialysis?
A recent paper, published in the Journal of Hepatology, has data from more than 45,000 Swedes with Hep C. The researchers found that among 268 people who underwent dialysis during the study’s long follow-up period, HPC was treated. Associated with an approximately 3-fold reduced risk of death compared to no treatment.
Meanwhile, the authors of a weighty new literature review and meta-analysis published in Annals of Hepatology examine the body of evidence available for analysis of HCV in addition to supporting the relationship between HCV, CVD and CKD. Prepare with a tooth comb. Marked effects on known metabolic factors, such as high blood pressure and cholesterol.
Hepatitis B And Your Cancer Risk
Examining a database of published research from 1989 to 2016, the researchers conducted a meta-analysis of 14 observational studies involving 145,000 people on long-term dialysis. They found that HCV positivity was an independent risk factor for death in this population; Specifically, hep C was associated with a 1.35-fold increased risk of mortality. However, the researchers could not determine whether this higher risk of death was driven solely by liver-related deaths. Nevertheless, they found that among those undergoing dialysis, the risk of liver-related death was increased 3.8 times in those with Hep C.
Additionally, after adjusting their data for several factors, the study authors found that among all people on dialysis, HCV was associated with a 1.21-fold increased risk of death from CVD.
The authors of the new paper theorize that the increased risk of CVD in dialysis recipients may result from insulin resistance, nonalcoholic fatty liver disease (NAFLD), or virus-driven inflammation. Insulin resistance and especially NAFLD can lead to several components of the metabolic syndrome (itself a CVD and CKD risk factor), including high blood pressure and dysregulated blood lipids, such as cholesterol.
Researchers behind a recent meta-analysis of 22 observational studies of 730,000 people adjusted their data for several factors and found that Hep C was associated with a 1.65-fold increased risk of dying from CVD, a 2.27 – Multiplication risk. 1.3 times greater risk of plaque in the carotid arteries and stroke.
However, it is important to consider that because the studies analyzed here are observational – they are not based on a randomized design – it is ultimately possible to make causal inferences between HCV and a particular health outcome based on their results. Impact is difficult to determine. Even when researchers adjust their data for differences between individuals, it is possible that there are non-HCV-related variables that are more common among people with the virus and are actually the main drivers of these health problems.
Despite this uncertainty, the study authors emphasize that traditional risk factors for CKD, such as aging (25 percent of people over 65 in Western countries have the disease), diabetes, high blood pressure and metabolic syndrome, do not fully explain why people with hep C have a higher CKD rate.
Recently, scientists have found evidence that Hep C is an independent risk factor for kidney disease. For example, the authors of the new paper conducted a meta-analysis of nine studies that included nearly 2 million individuals and found that HCV was associated with a 1.43-fold increased rate of CKD diagnosis.
These scientists also reviewed the available scientific literature to examine the association of HCV with diabetes. In a long-term study of nearly 5,000 individuals in Taiwan, researchers found that the virus was associated with a 1.7-fold increased risk of diabetes. This independent relationship between HCV and diabetes was particularly strong in those who were younger or had a higher body mass index (BMI). In a promising sign, people treated for Hep C saw a decrease in their insulin resistance (a major factor in diabetes) during and after treatment.
Hepatitis C Causes, Symptoms, And Treatments
So what does the medical literature say about how Hep C treatment may affect non-liver-related health and survival factors?
For starters, a retrospective study of nearly 200 people with hepatitis C in Taiwan, followed for nearly five years, indicated that treating the virus reduced the risk of stroke.
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