Does Coffee Affect Your Liver – A new study shows that drinking even a few glasses a day can prevent hardening of the liver, reports the
Chronic liver disease is the 12th leading cause of death worldwide and many of these diseases are linked to unhealthy lifestyles. On the contrary, a healthy lifestyle can help prevent or reverse liver disease. Liver-related death is closely related to the development of cirrhosis, the end result of progressive fibrosis, i.e. liver failure resulting from chronic inflammation. According to a new study published in the Journal of Hepatology, researchers found that drinking coffee and herbal tea can protect against liver fibrosis, which is estimated as the degree of stiffness of the -liver, which is high in many liver scars. Because these drinks are popular, widely available, and inexpensive, they may have the potential to be important in preventing advanced liver disease.
Does Coffee Affect Your Liver
“Over the past few decades, we have gradually drifted into more unhealthy habits, including a sedentary lifestyle, reduced physical activity, and ‘Happy Diet’ consumption,” explains lead author Louise J. M. Alferink, MD, of the Department of Gastroenterology and Hepatology. , Erasmus MC University Medical Center, Rotterdam, The Netherlands, “This Happy Meal, also known as the Western diet, is often rich in unhealthy foods including processed foods that lack nutrients and artificial sugars .This has led not only to an epidemic of obesity. , but also to a rapid increase in the prevalence of non-alcoholic fatty liver disease (NAFLD), which is caused by the extensive accumulation of fat in the liver and is similar to alcoholic liver disease in people who do not exceed two drinks a day of alcohol. In this context, the examination of fast and cheap lifestyle strategies with potential health benefits, such as coffee and tea consumption, is a practical approach to finding ways to prevent the rapid increase in liver disease in developed countries.
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Sarwa Darwish Murad, MD, PhD, principal investigator of the study and hepatologist at the Erasmus MC University Medical Center, continued “There is some epidemiological, but also experimental data that suggests that coffee has health benefits for elevations of liver enzymes, viral hepatitis, NAFLD. , cirrhosis, and liver cancer. Beyond the liver, coffee has been shown to be inversely associated with total mortality in the general population. The exact mechanism is unknown but it is believed that coffee has an anti-oxidant effect. We were interested to know if the consumption of coffee has the same effect on the measurement of liver stiffness in individuals without liver disease.
Data were obtained from 2,424 participants in the Rotterdam study, a large population-based cohort study including participants aged 45 years or older living in a suburb of Rotterdam, the Netherlands. All participants underwent an extensive physical workup, including data collection for anthropometry, blood sampling, hepatological imaging using abdominal ultrasound and Fibroscan®, which quantitatively measures the stiffness of -liver. In addition, they completed an externally validated 389-item Food Frequency Questionnaire, which included detailed information on coffee and tea consumption.
Total coffee and tea consumption was divided into three categories: none, moderate (>0-3 cups per day), and frequent (≥3). Tea consumption was categorized into herbal, green or black tea plus no consumption (0) or any (>0).
Using data from the Rotterdam Study researchers determined that regular coffee and herbal tea consumption was inversely associated with liver stiffness but not steatosis in the general population. Credit: L. Alferink and S. Darwish Murad.
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The investigators found that frequent coffee consumption was significantly associated with a lower probability of high values ​​of liver stiffness​​(≥8 kPa as a proxy for liver fibrosis), i.e. less liver scarring, independent of lifestyle, metabolic and environmental characteristics. When they looked at the total values ​​of liver stiffness, they found that regular coffee and any consumption of herbal tea, even in small amounts, were associated with lower values ​​of liver stiffness. Finally, while no direct association was found between coffee or tea and the presence of fatty liver accumulation (NAFLD) per se, the effect of coffee on the reduction of stiffness of the liver was significant in the group with and without fat in the liver. The authors therefore concluded that regular coffee and herbal tea appear to have beneficial effects in preventing liver scarring even before overt liver disease develops.
However, some caution is required in the interpretation of the results, as noted in the accompanying editorial by Salvatore Petta, MD, PhD, of the Gastroenterology and Hepatology Section, Di.Bi.M.I.S., University of Palermo, l -Italy, and Giulio Marchesini , MD, of the Department of Medical and Surgical Sciences (DIMEC), University “Alma Mater”, Bologna, Italy., In fact, the study included only an elderly Caucasian population and was there are few participants without coffee or not. – tea control groups, which will limit a simple conclusion about the effect of coffee and tea on the liver.. The amount of tea consumed is generally low, to make the estimate of any protective effect is difficult In addition, they noted that more than 100 substances are present in coffee and tea, including polyphenols and caffeine, which are present in the same drinks in very different and different amounts.
Therefore, when asked “Should we add regular coffee and tea breaks to our daily lives? The conclusion of Dr. Petta and Dr. Marchesini is, “Before this policy can be recommended, studies are needed futures to determine the best amount and type. (s) of coffee and tea leading to better liver results.”
The article is “Coffee and Herbal Tea Consumption Is Associated with Lower Stiffness of the Liver in the General Population: The Rotterdam Study,” by Louise Johanna Maria Alferink, MD; Juliana Fittipaldi; Jessica C. Kiefte-de Jong, RD, PhD; Pavel Taimr, MD; Bettina E. Hansen, PhD; Herold J. Metselaar, Prof. MD; Josje D. Schoufour, PhD; Arfan M. Ikram, MD, PhD; Harry L. Janssen, Prof. MD; Oscar H. Franco, Prof. MD; and Sarwa Darwish Murad, MD, PhD (https://dx.doi.org/10.1016/j.jhep.2017.03.013). The editorial is “Coffee and Tea Breaks for Liver Health,” by Salvatore Petta, MD, PhD, and Giulio Marchesini, MD (https://dx.doi.org/10.1016/j.jhep.2017.04.014). Both contributions were published in
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The full text of these articles is available to credentialed journalists upon request; contact Sybrand Boer Iwema on +31 20 485 2781 or hmsmedia@. Journalists wishing to interview the authors of the article should contact Sarwa Darwish Murad on +31 628021137 or +31 107035942 (secr.) or [email protected]. Contact Salvatore Petta on +39 091 655 2170 or s[email protected] regarding editorial. For questions about
Is the official journal of the European Association for the Study of the Liver (EASL). It publishes original papers, reviews, case reports, and letters to the Editor related to clinical and basic research in the field of hepatology. www.journal-of-hepatology.eu
In the forty years and more since EASL was founded, it has grown from a small organization that welcomed 70 participants at its first meeting, to becoming the main liver association in Europe. EASL attracts leading experts in hepatology as members and has an impressive record of promoting liver disease research, supporting wider education and advocating for changes in European health policy. liver. www.easl.eu
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You probably don’t need much convincing when it comes to the benefits of drinking coffee. Not only is it delicious, but it can give you a much-needed boost of energy on a sleepy morning or afternoon, and it’s even known to reduce your risk of heart disease and diabetes. What some people don’t realize, however, is that coffee can also improve your liver health.
Research continues
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