Does Aleve Affect Your Kidneys – If we eat Everything we drink or inject into our body circulates in our blood through our kidneys. This concept also applies to drugs.
You all know that prescription drugs come with specific dosing instructions. They comply with dosing protocols that have been proven to be “safe and effective” after rigorous clinical trials of the drug. The goal of this fixed dosing regimen is to maximize the benefit of the drug and minimize the risk of harmful side effects.
Contents
- 1 Does Aleve Affect Your Kidneys
- 2 These Symptoms Can Mean You Have Kidney Damage
- 3 Kidney Damage From Nonsteroidal Anti‐inflammatory Drugs—myth Or Truth? Review Of Selected Literature
- 4 Are You Among The 1 In 3 People At Risk For Kidney Disease?
- 5 Naproxen Vs. Ibuprofen: Which Is The Better Nsaid Pain Reliever?
- 6 Naproxen: Uses, Side Effects, Dosage, Warnings, And Interactions
Does Aleve Affect Your Kidneys
If you don’t follow your doctor’s instructions or if it is an illegal drug, it can damage your kidneys.
These Symptoms Can Mean You Have Kidney Damage
This article aims to provide an overview of which drugs can cause nephrotoxicity (kidney damage).
Our kidneys work tirelessly 24/7 to filter and balance 100% of our blood. It allows all organs to carry out all their normal functions. Of this, 20% of pure blood is used by the kidneys themselves. Are you wondering why? Since this kidney filter contains millions of organisms, This is because respiration and the cells themselves are actively subjected to metabolic processes and need nutrients just like the cells of all other organs.
Such severe exposure of kidney cells to our bloodstream also negatively affects these cells due to unwanted changes in the blood.
As detailed in the following section, excessive or long-term use of certain medications or drugs (illegal drugs) can cause harmful chemicals to build up in the blood and alter its composition. These chemicals can damage the kidneys.
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Many known kidney-damaging drugs are actually safe at clinically approved “therapeutic” dosages and durations because kidney function is normal. Here are four ways drugs can damage your kidneys:
Chronic use of prescription drugs intended for short periods of time (e.g., painkillers, antacids) without consulting your doctor.
The kidney is made up of billions of cells that can be classified into 26 different types. All this is done by the delicate kidney filters (Nephrons). It is made up of over 1 million blood vessels and supporting tissues. There are many ways that drugs can damage your kidneys.
Now that you have some perspective on what the nephron looks like, let’s look at how kidney-damaging drugs can affect your kidneys one by one.
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As it passes through the body through urine, some drug metabolites can inhibit the ability of tubular cells to remove excess acid from a person’s bloodstream.
As a result, patients with metabolic acidosis can damage the nerves and heart and worsen kidney function.
These can block the flow of urine to reduce pressure on kidney cells. These crystals can also “drive and lodge in the renal cell mass” to inflame kidney tissue.
Below, find a list of drugs that can cause kidney damage and harm based on their medical use.
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To see if the brand of medicine can cause kidney damage, look for its “composition” printed on the medicine package/container and compare it to the list below.
Painkillers usually belong to the class of NSAIDs. With normal kidney function, these drugs should not be taken for more than 10 days in case of pain and 3 days in case of illness.
Otherwise it is Acute Tubular Necrosis. Kidney damage can occur with acute kidney injury, glomerulonephritis, chronic interstitial nephritis or rhabdomyolysis. Such pain relievers include, but are not limited to;
Some blood pressure medications used for kidney disease can damage the kidneys if doses are not adjusted accordingly.
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The following classes of drugs help regulate blood pressure by modulating blood flow to the kidneys. These drugs may cause acute kidney injury (AKI) if increased abnormally due to long-term use or poor excretion (such as kidney disease).
Diuretics or “water pills” are medications used to treat excess fluid in the body. These drugs are used for kidney disease, hypertension. It can be given to patients with heart disease or advanced liver disease.
Long-term use of the following diuretics may cause kidney damage due to renal tubular acidosis and acute interstitial nephritis.
Heartburn is a common problem throughout the world. incorrect eating habits/lifestyle; acid reflux disease (GERD); It could be due to obesity or side effects of other medications.
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However, unless advised by your doctor. It is best not to rely on drugs that reduce acidity in the long term. This is because they have been found to affect kidneys affected by acute interstitial nephritis.
Antibiotics or antimicrobials prescribed to treat infections have a specific dose and duration. Most of it is eliminated from the body through the kidneys in urine.
Patients should not take these medications without supervision or use them excessively for long periods of time. Other kidneys may be severely affected. The damage is glomerulonephritis, Acute tubular necrosis; It can range from crystal nephropathy to acute interstitial nephritis.
Some antiviral drugs can seriously damage your kidneys, especially if you already have chronic kidney disease. Your doctor needs to know the health of your kidneys.
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After “systemic” metabolism, oral antifungal agents are eliminated via the kidneys in the urine. In the process, some people may have kidney damage with acute tubular necrosis and renal tubular acidosis that increase the acidity of the blood.
Diabetes medications work through several mechanisms to keep blood glucose levels under control. Most of these mechanisms are directly related to the kidneys.
These drugs must be taken long-term, so your kidneys may stop working.
As a result, Finally, excessive water retention in the blood, which burdens the kidneys; Urinary sodium: excessive loss of key minerals; Sudden excessive protein loss may occur due to high blood acidity or nephrotic syndrome. Common diabetes medications that cause such concerns include:
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This is another type of drug prescribed long-term and requires continuous monitoring of patients for adverse effects on the kidneys.
Drugs for kidney damage with bone/joint disorders, thrombotic microangiopathy, Glomerulonephritis Crystal nephropathy; Acute interstitial nephritis; Nephrotic syndrome can progress over time from membranous nephropathy to chronic kidney disease.
Some drugs used to treat depression and psychosis can damage kidney health if taken long-term. They are rhabdomyolysis, It can damage the kidneys through glomerulonephritis and chronic interstitial nephritis.
Drugs used in cancer chemotherapy are known to damage the kidneys. These include thrombotic microangiopathy, glomerulonephritis, crystal nephropathy; It can do this by causing chronic interstitial nephritis and hemorrhagic cystitis (inflammation and bleeding of the cyst). Most concerns are:
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Some medications are drugs that suppress the immune system. They can help reduce unwanted inflammation if you suffer from autoimmune disorders or to prevent your body from rejecting or receiving an organ transplant.
If possible Your doctor may also give you a blood test to check the amount of these drugs in your body. This is to reduce the possibility of adverse effects.
Chronic high doses of the immunosuppressive drugs listed below; Metabolic acidosis in overdose or unmonitored; Acute tubular necrosis; Acute interstitial nephritis; Thrombotic microangiopathy and hypertension can cause kidney damage.
The FDA has raised an alert about acute kidney injury linked to the use of some prescription laxatives.
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Chronic overdose or high doses before colonoscopy can damage kidney health, especially if you already have kidney disease.
Herbal supplements sold throughout the world in various systems of traditional medicine are generally not subjected to the regulatory approval evaluation that allopathic medicines are subjected to. The clear purpose of these regulations is to establish how “safe” and “effective” a drug is. The lack of such regulatory studies means that there is absolutely no evaluation of the potential side effects of herbal supplements. I can’t prove how safe it is.
Some traditional herbal supplements may contain aristolochic acid. Patients taking these herbs have been found to develop chronic interstitial nephritis.
2. Plants of the genus Aristolochiaceae used in homeopathic and traditional Chinese medicine as analgesics and antihypertensives:
Acute Kidney Failure
MRI CT scan IVP Some diagnostic tests called “imaging tests,” such as angiograms or barium scans, may use “radioactive dye.”
The purpose of this dye is to improve the quality of medical imaging and help improve diagnosis and treatment planning.
However, for patients at risk of kidney damage due to contrast dyes, it is important to evaluate the benefits of using these dyes:
The obvious reason is that in high-risk patients, some contrast dyes can cause kidney damage through acute tubular necrosis and acute kidney injury.
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There is a special name for acute kidney injury (AKI) caused by radioactive dye. This is contrast-induced nephropathy (CIN).
Additionally, Separate, which may include the use of contrast dyes in patients with kidney disease. There is also a broader side effect. It is called nephrogenic systemic fibrosis (NSF). Read more about these.
Drinking heavily and regularly (about 5 drinks per day as the 1 drink standard described here) can damage both kidneys through acute tubular necrosis or renal failure.
အချို့သောတရားမ၀င် “အရူး” ဆေးဝါးများသည် သင့်က ြွက်သားများဆီသို့ သွေးစီးဆင်းမှုကို ရုတ်ခြ ည်း ဖြတ်တောက်နိုင်ပြီး ကြွက်သားမျှင်များ၏ လ ှုပ်ရှားမှုလွန်ကဲမှုကို တွန်းအားပေးနိုင်သည ်။
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ထိုကဲ့သို့သော ကြွက်သားများ ပြိုကွဲစေသော ထု တ်ကုန်များကို ပုံမှန်အားဖြင့် ဆီးမှတစ်ဆင့် သင့်ကျောက်ကပ်မှတဆင့် ခန္ဓာကိုယ်မှ ဖယ်ရှားပ ါသည်။ ဒါတွေက မင်းရဲ့ သိမ်မွေ့တဲ့ ကျောက်ကပ်အတွက် အ လွန်ကြမ်းတမ်းပါတယ်။
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